Mount Sinai Researchers Unveil Mechanisms to Prevent Crohn’s Disease; Studies Describe Predictive Tools and Triggering Environmental Risk Factors Key to Prevention

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In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.

In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.

“Early identification of individuals at high risk for disease development could allow for close monitoring and interventions to delay, attenuate, or even halt disease initiation. This is highly relevant as we seek to predict and prevent IBD, which continues to sharply increase in numbers across the globe,” says Jean-Frederic Colombel, MD, Professor of Medicine (Gastroenterology) at the Icahn School of Medicine at Mount Sinai and Co-Director of Mount Sinai’s Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center. “In the absence of a cure, our clinical strategy will center on aggressive and innovative mechanisms to predict and prevent the disease,” says Dr. Colombel.

The series of papers published in Gastroenterology provide four unique windows into IBD through the single lens of prevention. “As we approach nearly one hundred years since the discovery of Crohn’s by Burrill Crohn at Mount Sinai Hospital in 1932, we see ourselves in a new era where our core scientific innovation will focus on prevention, as a cure continues to elude us. Therefore, our research focus and our team of researchers are aligned as the “Road to Prevention Group,” says Dr. Colombel.

Read more at The Mount Sinai Hospital / Mount Sinai School of Medicine