Microbiome Breakthrough: Gut Bacterium May Hold Key to Future Treatments for Widespread Chronic Diseases

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Our intestines are home to trillions of microorganisms that produce substances capable of regulating all the body’s organs via the bloodstream and the gut’s nervous system.

Our intestines are home to trillions of microorganisms that produce substances capable of regulating all the body’s organs via the bloodstream and the gut’s nervous system. Yet, only little is known about the effects of most of the bacteria that make up our microbiome. Now, an international team of scientists led by the University of Copenhagen has identified a common specific bacterial strain that may open the door to an entirely new class of therapeutics.

This bacterium produces two proteins that partly resemble the hormone irisin. Irisin is released by muscles during physical activity and plays a role in fat metabolism.

The newly discovered signaling proteins, named RORDEP1 and RORDEP2, influence the body’s hormonal balance and affect weight, bone density, and blood sugar levels.

Read More: University of Copenhagen