Researchers have shown for the first time how children can inherit a severe – potentially fatal – mitochondrial disease from a healthy mother. The study, led by researchers from the MRC Mitochondrial Biology Unit at the University of Cambridge, reveals that healthy people harbour mutations in their mitochondrial DNA and explains how cases of severe mitochondrial disease can appear unexpectedly in previously unaffected families.
articles
Discovery of a new source of world's deadliest toxin
Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow’s gut.
This is the first time that an intact cluster of genes for making botulinum neurotoxin have been found outside of the bacterium Clostridium botulinum or its close relatives, and only the second report of a new botulinum toxin in the past 40 years.
Jet Stream Changes Since 1960s Linked to More Extreme Weather
Increased fluctuations in the path of the North Atlantic jet stream since the 1960s coincide with more extreme weather events in Europe such as heat waves, droughts, wildfires and flooding, reports a University of Arizona-led team.
The research is the first reconstruction of historical changes in the North Atlantic jet stream prior to the 20th century. By studying tree rings from trees in the British Isles and the northeastern Mediterranean, the team teased out those regions' late-summer weather going back almost 300 years — to 1725.
Robots aid better understanding of phytoplankton blooms
Phytoplankton blooms are one of the most important factors contributing to the efficiency of the carbon pump in the North Atlantic Ocean. To better understand this phenomenon, the ERC remOcean1 project, led by researchers at the Laboratoire d'Océanographie de Villefranche (CNRS/UPMC), has developed a new class of robots: biogeochemical profiling floats, the first robots able to collect data in the ocean throughout the year. Using these unparalleled data, the researchers have identified the starting point for the explosive spring phytoplankton bloom. Their results are the subject of two articles published in Nature Geoscience and Nature Communications.
Flu Vaccine Spinout Secures a Further £20m in Funding
Vaccitech, an Oxford University spinout company developing a universal flu vaccine, among other vaccine-related products, has secured £20 million in Series A financing.
UCLA scientists make cells that enable the sense of touch
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have, for the first time, coaxed human stem cells to become sensory interneurons — the cells that give us our sense of touch. The new protocol could be a step toward stem cell–based therapies to restore sensation in paralyzed people who have lost feeling in parts of their body.