Researchers have devised a medicated skin patch that can turn energy-storing white fat into energy-burning brown fat locally while raising the body’s overall metabolism. The patch could be used to burn off pockets of unwanted fat such as “love handles” and treat metabolic disorders, such as obesity and diabetes, according to researchers at Columbia University Medical Center (CUMC) and the University of North Carolina.

For several years, medical researchers, doctors and dieticians have known that a low carbohydrate diet and plentiful fat can prevent a range of lifestyle and age-related diseases and thus promote healthy aging. But researchers from around the world have not been able to explain why this is the case. They have just been reasonably certain that the energy metabolism and its chemical intermediates (metabolites) play a central role.

MIT engineers have invented a new 3-D fabrication method that can generate a novel type of drug-carrying particle that could allow multiple doses of a drug or vaccine to be delivered over an extended time period with just one injection.

The new microparticles resemble tiny coffee cups that can be filled with a drug or vaccine and then sealed with a lid. The particles are made of a biocompatible, FDA-approved polymer that can be designed to degrade at specific times, spilling out the contents of the “cup.”

A new study evaluating models of future climate scenarios has led to the creation of the new risk categories “catastrophic” and “unknown” to characterize the range of threats posed by rapid global warming. Researchers propose that unknown risks imply existential threats to the survival of humanity.

These categories describe two low-probability but statistically significant scenarios that could play out by century’s end, in a new study by Veerabhadran Ramanathan, a distinguished professor of climate and atmospheric sciences at Scripps Institution of Oceanography at the University of California San Diego, and his former Scripps graduate student Yangyang Xu, now an assistant professor at Texas A&M University.

Using ethanol instead of gasoline as a car fuel can reduce emissions of ultrafine particles by a third, which benefits human health and the environment, according to a new study.

Feel like everyone else has more friends than you do? You’re not alone— but merely believing this is true could affect your happiness.

A “look back” analysis of more than 600 major colorectal surgeries using a “checklist” tool has added further evidence that racial and socioeconomic disparities may occur during many specific stages of surgical care, particularly in pain management.

Adapting to the microgravity environment of space changes the way your brain interprets sensory signals, decreases muscle strength and alters cardiovascular function. Astronauts will need to overcome these changes to perform critical mission tasks on a journey to Mars. Simple tasks on Earth such as exiting a vehicle becomes more crucial when stepping foot in an unfamiliar world. Maintaining balance control will be key to a successful mission.

There's been a lot of interest in the harmful effects of prolonged sitting at work, from academics and the public alike. The attention being paid to sitting – or rather, not sitting – while on the job stems from the scientifically validated message that being sedentary in general, both indoors and outdoors, is bad for your health.

However, comparatively little attention has been devoted to the harmful effects of prolonged standing at work, despite past studies linking it to chronic back pain and musculoskeletal disorders (MSDs) in the lower limbs.

Human populations have always been exposed to ionizing radiation, and more so in modern life due to its use in medicine, industry and the armed forces. Whilst the risks to human health from medium and high-level radiation are relatively well-understood, the risks at lower levels are less clear.  Mixed messages about the safety of low doses of radiation from different sources have created confusion for the public and for policy makers.