• Sowing Stem Cells: Lab-Grown Organoids Hold Promise for Patient Treatments

    Ophir Klein is growing teeth, which is just slightly less odd than what Jeffrey Bush is growing – tissues that make up the face. Jason Pomerantz is growing muscle; Sarah Knox is growing salivary glands; and Edward Hsiao is printing 3-D bone using a machine that looks about as complex as a clock radio.

    Together, these members of the UC San Francisco faculty are cultivating organs of the craniofacial complex – the skull and face – which too often go terribly wrong during fetal development. Deformities of these bones or soft tissues, the most common of birth defects, can cut life short by blocking the airway or circulation. Or they can disfigure a face so profoundly that a child struggles to see, hear, or talk. Perhaps most painful of all, such deformities render children physically other, potentially leading to a lifetime of corrective surgeries and social isolation.

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  • Study Identifies an Enzyme Inhibitor to Treat Gulf War Illness Symptoms

    At least 100,000 military veterans who served in the 1990-1991 Gulf War were exposed to chemical weapons, released into the air after the United States bombed an ammunition depot in Khamisiyah, Iraq. Today, many are still suffering from Gulf War Illness, a mysterious, multi-symptom disease that experts believe is linked to organophosphate nerve agents sarin and cyclosarin.

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  • Variable Speed Limits Could Reduce Crashes, Ease Congestion in Highway Work Zones

    As the summer months approach, most people turn to thoughts of sunshine, outdoor barbecues and destination trips. Yet travelers often are greeted by detours, lane closures and delays for road repairs that generally are reserved for warmer weather. Researchers at the University of Missouri have studied systems to alleviate inevitable backups and delays. Researchers found that using variable speed limits in construction zones may ease congestion, reduce crashes and make work zones safer for both workers and travelers nationally.

    With assistance from the Missouri Department of Transportation, Praveen Edara, associate professor of civil and environmental engineering in the MU College of Engineering, tested the use of variable advisory speed limit (VASL) systems and the effect they may have on lessening congestion and reducing rear-end and lane-changing accidents on a fairly dangerous stretch of I-270, a major four-lane highway in St. Louis.

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  • How killer cells take out tumours

    The use of immunotherapy to treat cancer is celebrating its first successes – but there are still many knowledge gaps in the underlying mechanisms of action. In a study of mice with soft tissue tumours, ETH researchers have now shown how endogenous killer cells track down the tumours with the help of dormant viruses.

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  • University of Toronto scientists develop custom-engineered protein to battle MERS virus

    In 2012, a 60-year-old man with flu-like symptoms died in Saudi Arabia, becoming the first victim of the Middle East Respiratory Syndrome or MERS.

    Until now, there has been no vaccine or known treatment. That could change thanks to a new anti-viral tool, developed by University of Toronto researchers.

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  • Web-Based System for Self-Reporting Symptoms Helps Patients Live Longer

    “Online technologies have transformed communications in practically every aspect of our lives, and now we’re seeing they’re also allowing patients to take an active role in their care and get immediate access to their care provider,” said ASCO Expert Harold J. Burstein, MD, PhD, FASCO. “It’s impressive that something as simple as this not only improves quality of life, but in this case, helps patients live longer. I think we’ll soon see more cancer centers and practices adopting this model.”

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  • Antibiotic-Resistant Bacteria in Ready-to-Eat Foods

    Research presented at the ASM Microbe 2017 meeting by Bryan Sanchez of California State University–Northridge in Northridge, Calif., show that antibiotic-resistant bacteria are present in many ready-to-eat foods such as fresh produce and dairy products and may serve as a source of human exposure to antibiotic-resistant bacteria. About 2 million people become infected with antibiotic resistant-bacteria annually in the United States, resulting in over $35 billion in additional health care costs. Examining potential ways that humans can be exposed to antibiotic-resistant bacteria can help in understanding how to counter the threat.

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  • Unconventional Oil and Gas Production Not Currently Affecting Drinking Water Quality

    Decades or longer may be needed to fully assess the effects of unconventional oil and gas production on the quality of groundwater used for drinking water in Arkansas, Louisiana, and Texas

    A new U.S. Geological Survey study shows that unconventional oil and gas production in some areas of Arkansas, Louisiana, and Texas is not currently a significant source of methane or benzene to drinking water wells. These production areas include the Eagle Ford, Fayetteville, and Haynesville shale formations, which are some of the largest sources of natural gas in the country and have trillions of cubic feet of gas.

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  • Study targets resiliency among aging Canadians with multiple illnesses

    Simon Fraser University researchers are investigating why some older Canadians living with multiple chronic health conditions maintain their resiliency.

    Professor Andrew Wister, director of SFU’s Gerontology Research Centre, is SFU’s principal investigator for the multi-university Canadian Longitudinal Study on Aging (CLSA). He leads one of 25 research teams benefiting from a share of $1.7 million in CLSA catalyst grants, funded by the Canadian Institutes of Health Research (CIHR), announced today.

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  • Immune responses from early study of novel sarcoma vaccine

    The critical component of an experimental vaccine led to an escalating immune response in patients with sarcoma, an indicator of its potential anti-cancer effects.

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