Can’t Sleep? Could Be Down to Genetics

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Researchers have identified specific genes that may trigger the development of sleep problems, and have also demonstrated a genetic link between insomnia and psychiatric disorders such as depression, or physical conditions such as type 2 diabetes. The study​​​​​​​ in the journal Molecular Psychiatry​​​​​​​, which is published by Springer Nature, was led by Murray Stein of the University of California San Diego and the VA San Diego Healthcare System.

Researchers have identified specific genes that may trigger the development of sleep problems, and have also demonstrated a genetic link between insomnia and psychiatric disorders such as depression, or physical conditions such as type 2 diabetes. The study​​​​​​​ in the journal Molecular Psychiatry​​​​​​​, which is published by Springer Nature, was led by Murray Stein of the University of California San Diego and the VA San Diego Healthcare System.

Up to 20 percent of Americans and up to 50 percent of US military veterans are said to have trouble sleeping. The effects insomnia has on a person’s health can be debilitating and place a strain on the healthcare system. Chronic insomnia goes hand in hand with various long-term health issues such as heart disease and type 2 diabetes, as well as mental illness such as post-traumatic stress disorder (PTSD) and suicide.

Twin studies have in the past shown that various sleep-related traits, including insomnia, are heritable. Based on these findings, researchers have started to look into the specific gene variants involved. Stein says such studies are important, given the vast range of reasons why people suffer from insomnia, and the different symptoms and varieties of sleeplessness that can be experienced.

“A better understanding of the molecular bases for insomnia will be critical for the development of new treatments,” he adds.

Read more at Springer

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