The Meat Allergy: UVA IDs Biological Changes Triggered by Tick Bites

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A School of Medicine scientist has identified key immunological changes in people who abruptly develop an allergic reaction to mammalian meat, such as beef.

A School of Medicine scientist has identified key immunological changes in people who abruptly develop an allergic reaction to mammalian meat, such as beef. His work also provides an important framework for other scientists to probe this strange, recently discovered allergy caused by tick bites.

The findings by UVA’s Loren Erickson, PhD, and his team offer important insights into why otherwise healthy people can enjoy meat all their lives until a hot slab of ground beef or a festive Fourth of July hot dog suddenly become potentially life-threatening. Symptoms of the meat allergy can range from mild hives to nausea and vomiting to severe anaphylaxis, which can result in death.

“We don’t know what it is about the tick bite that causes the meat allergy. And, in particular, we haven’t really understood the source of immune cells that produce the antibodies that cause the allergic reactions,” Erickson explained. “There’s no way to prevent or cure this food allergy, so we need to first understand the underlying mechanism that triggers the allergy so we can devise a new therapy.”

Read more at: University of Virginia Health System

The new discovery by UVA's Loren Erickson, PhD, is an important step toward understanding the strange meat allergy spread by ticks -- and developing a treatment for it. (Photo Credit: UVA Health)