Diagnosing Parkinson’s Disease with Skin Samples Could Lead to Earlier Detection

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New research shows a simple skin test can accurately identify Parkinson’s disease, demonstrating for the first time the feasibility of the method.

New research shows a simple skin test can accurately identify Parkinson’s disease, demonstrating for the first time the feasibility of the method. Currently diagnosed by clinical signs and symptoms but only definitively diagnosed at autopsy, Parkinson’s disease is commonly misdiagnosed early in the disease course, complicating clinical trials of potential treatments.

The study, published in the scientific journal Movement Disorders, shows how a chemical assay can detect clumping of the protein alpha-synuclein in skin samples to help diagnose Parkinson’s disease (PD). The study’s authors said using the assay can lead to earlier detection of PD and better clinical trials.

“Since there’s no easy and reliable test available for the early diagnosis of Parkinson’s disease at present, we think there will be a lot interest in the potential use of skin samples for diagnosis,” said Anumantha Kanthasamy, Distinguished Professor of Biomedical Sciences at Iowa State and lead author of the study.

Read more at: Iowa State University

Anumnatha Kanthasamy (Photo Credit: Iowa State University News Service)