Bioengineered Cornea Can Restore Sight to the Blind and Visually Impaired

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Researchers and entrepreneurs have developed an implant made of collagen protein from pig’s skin, which resembles the human cornea. 

Researchers and entrepreneurs have developed an implant made of collagen protein from pig’s skin, which resembles the human cornea. In a pilot study, the implant restored vision to 20 people with diseased corneas, most of whom were blind prior to receiving the implant.

The study jointly led by researchers at Linköping University (LiU) and LinkoCare Life Sciences AB has been published in Nature Biotechnology. The promising results bring hope to those suffering from corneal blindness and low vision by providing a bioengineered implant as an alternative to the transplantation of donated human corneas, which are scarce in countries where the need for them is greatest.

“The results show that it is possible to develop a biomaterial that meets all the criteria for being used as human implants, which can be mass-produced and stored up to two years and thereby reach even more people with vision problems. This gets us around the problem of shortage of donated corneal tissue and access to other treatments for eye diseases”, says Neil Lagali, professor at the Department of Biomedical and Clinical Sciences at LiU, one of the researchers behind the study.

Read more at Linköping University

Image: In a pilot study, the implant restored vision to 20 people with diseased corneas, most of whom were blind prior to receiving the implant. (Credit: Thor Balkhed/Linköping University)