A ‘Double-Punch’ Approach to Tackling Brain Cancer

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Light-activated nanoparticles could help surgeons see glioblastoma more clearly and destroy cancer cells left behind after surgery.

Light-activated nanoparticles could help surgeons see glioblastoma more clearly and destroy cancer cells left behind after surgery.

Glioblastoma is the most aggressive form of brain cancer, which has recently come into the spotlight in Australia with the diagnosis and subsequent experimental treatment for the late Richard Scolyer.

It’s difficult to treat because tumour cells infiltrate the surrounding brain tissue, making it hard for surgeons to remove the cancer completely without damaging healthy tissue. Treatment is complicated further by the blood-brain barrier, which limits how well drugs and radiotherapy reach the brain. All these factors contribute to a five-year survival rate of only around 7 per cent.

Researchers from the University of Technology Sydney (UTS), Harvard and Henan universities have discovered a ‘double-punch’ nanozyme platform designed to address both problems with a single tool of smart nanoparticles, published in Science Translational Medicine.

Read More: University of Technology Sydney

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