OHSU scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people – a finding that holds promise for developing new gene therapies to treat Batten disease.

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent painful swellings of the skin and mucous membranes. Without treatment, patients’ quality of life is noticeably compromised: Angioedema may not only be disfiguring; in the gastrointestinal tract it may lead to severe abdominal colic ad in the upper airways it can even be fatal if left untreated. The frequency of angioedema attacks is unpredictable and varies from patient to patient; swellings may occur up to several times a week. The disorder affects about one to two in a hundred thousand people. 

The role of the e-bike in promoting health and fitness is comparable to that of a conventional bicycle. This was reported by researchers of the University of Basel in the Clinical Journal of Sport Medicine. In particular, overweight and untrained individuals can benefit from riding an e-bike.

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects.

Rice University scientists have released the first results of extensive water sampling in Houston after the epic flooding caused by Hurricane Harvey. They found widespread contamination by E. coli, likely the result of overflow from flooded wastewater treatment plants.

New-generation lung cancer drugs have been effective in a large number of patients, but within about a year, the patients tend to develop resistance to the therapy. Researchers at the Weizmann Institute of Science, in collaboration with physicians, have conducted a study in mice, in which they used existing drugs in a new combination to help crush potential resistance to the treatment. Their findings were published recently in the journal Clinical Cancer Research.

Many city drinking water systems add softening agents to keep plumbing free of pipe-clogging mineral buildup. According to new research, these additives may amplify the risk of pathogen release into drinking water by weakening the grip that bacteria – like those responsible for Legionnaires’ disease – have on pipe interiors.

Researchers at MIT have created what may be the smallest robots yet that can sense their environment, store data, and even carry out computational tasks. These devices, which are about the size of a human egg cell, consist of tiny electronic circuits made of two-dimensional materials, piggybacking on minuscule particles called colloids.

Suicide rates are likely to rise as the earth warms, according to new research published July 23 in Nature Climate Change. The study, led by Stanford economist Marshall Burke, finds that projected temperature increases through 2050 could lead to an additional 21,000 suicides in the United States and Mexico.

Greening vacant urban land significantly reduces feelings of depression and improves overall mental health for the surrounding residents, researchers from the Perelman School of Medicine and the School of Arts & Sciences at the University of Pennsylvania and other institutions show in a new randomized, controlled study published in JAMA Network Open. The findings have implications for cities across the United States, where 15 percent of land is deemed “vacant” and often blighted or filled with trash and overgrown vegetation.