University of Houston researcher Chandra Mohan is reporting in Arthritis Research and Therapy that clotting proteins, both those that promote blood clots (pro-thrombotic) and those that work to dissipate them (thrombolytic), are elevated in the urine of patients who suffer from lupus nephritis (LN).

MIT computer scientists are hoping to accelerate the use of artificial intelligence to improve medical decision-making, by automating a key step that’s usually done by hand — and that’s becoming more laborious as certain datasets grow ever-larger.

Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.

Blood pressure monitoring might one day become as easy as taking a video selfie, according to new research in Circulation: Cardiovascular Imaging, an American Heart Association journal.

People who spend eight or more hours a day staring at a computer screen may notice their eyes becoming tired or dry, and, if those conditions are severe enough, they may eventually develop dry eye disease (DED).

Using genetic tools in mice, researchers at Johns Hopkins Medicine say they have identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells, are born in the mammalian inner ear. The proteins, described in a report published June 12 in eLife, may hold a key to future therapies to restore hearing in people with irreversible deafness.

“Scientists in our field have long been looking for the molecular signals that trigger the formation of the hair cells that sense and transmit sound,” says Angelika Doetzlhofer, Ph.D., associate professor of neuroscience at the Johns Hopkins University School of Medicine. “These hair cells are a major player in hearing loss, and knowing more about how they develop will help us figure out ways to replace hair cells that are damaged.”

In order for mammals to hear, sound vibrations travel through a hollow, snail shell-looking structure called the cochlea. Lining the inside of the cochlea are two types of sound-detecting cells, inner and outer hair cells, which convey sound information to the brain.

An estimated 90% of genetic hearing loss is caused by problems with hair cells or damage to the auditory nerves that connect the hair cells to the brain. Deafness due to exposure to loud noises or certain viral infections arises from damage to hair cells. Unlike their counterparts in other mammals and birds, human hair cells cannot regenerate. So, once hair cells are damaged, hearing loss is likely permanent.

Read more at: Johns Hopkins Medicine

Mouse cochlea with hair cells shown in green and auditory nerves shown in red. (Photo Credit: Doetzlhofer lab)

Eating dark chocolate may positively affect mood and relieve depressive symptoms, finds a new UCL-led study looking at whether different types of chocolate are associated with mood disorders.

A new Mayo Clinic research study shows that artificial intelligence (AI) can detect the signs of an irregular heart rhythm — atrial fibrillation (AF) — in an EKG, even if the heart is in normal rhythm at the time of a test. 

A new model developed at MIT can help predict if patients at risk for Alzheimer’s disease will experience clinically significant cognitive decline due to the disease, by predicting their cognition test scores up to two years in the future.

Depression affects more than 300 million people worldwide, and while Cognitive Behavioural Therapy (CBT) can be an effective treatment, it does not work for everyone (only 45% of patients).