• A new method of 3D printing living tissues

    The approach could revolutionise regenerative medicine, enabling the production of complex tissues and cartilage that would potentially support, repair or augment diseased and damaged areas of the body.

    Printing high-resolution living tissues is hard to do, as the cells often move within printed structures and can collapse on themselves. But, led by Professor Hagan Bayley, Professor of Chemical Biology in Oxford’s Department of Chemistry, the team devised a way to produce tissues in self-contained cells that support the structures to keep their shape.

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  • Mercury is altering gene expression

    The mercury found at very low concentrations in water is concentrated along the entire food chain, from algae via zooplankton to small fish and on to the largest fish — the ones we eat. Mercury causes severe and irreversible neurological disorders in people who have consumed highly contaminated fish. Whereas we know about the element’s extreme toxicity, what happens further down the food chain, all the way down to those microalgae that are the first level and the gateway for mercury? By employing molecular biology tools, a team of researchers from the University of Geneva (UNIGE), Switzerland, has addressed this question for the first time. The scientists measured the way mercury affects the gene expression of algae, even when its concentration in water is very low, comparable to European environmental protection standards. Find out more about the UNIGE research in Scientific Reports.

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  • Air pollution linked to cardiovascular disease; air purifiers may lessen impact

    Exposure to high levels of air pollution increased stress hormone levels and negative metabolic changes in otherwise healthy, young adults in a recent study conducted in China. Air purifiers appeared to lessen the negative effects, according to new research published in the American Heart Association’s journal Circulation.

    Researchers focused on fine particulate matter (PM2.5) – a component of air pollution emitted from vehicles, factories, power plants, fires and smoking – because many studies have suggested this type of major air pollutant might lead to cardiovascular and metabolic health consequences, according to Haidong Kan, M.D., Ph.D., study author and professor of environmental health sciences at Fudan University in Shanghai, China.

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  • Lights, camera, CRISPR: Biologists use gene editing to store movies in DNA

    Internet users have a variety of format options in which to store their movies, and biologists have now joined the party. Researchers have used the microbial immune system CRISPR–Cas to encode a movie into the genome of the bacterium Escherichia coli.

    The technical achievement, reported on 12 July in Nature, is a step towards creating cellular recording systems that are capable of encoding a series of events, says Seth Shipman, a synthetic biologist at Harvard Medical School in Boston, Massachusetts. While studying brain development, Shipman became frustrated by the lack of a technique to capture how cells in the brain take on distinct identities. This inspired him to explore the possibility of making cellular recorders.

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  • Feeling bad about feeling bad can make you feel worse

    Pressure to feel upbeat can make you feel downbeat, while embracing your darker moods can actually make you feel better in the long run, according to new UC Berkeley research.

    “We found that people who habitually accept their negative emotions experience fewer negative emotions, which adds up to better psychological health,” said study senior author Iris Mauss, an associate professor of psychology at UC Berkeley.

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  • Pennsylvania Hospital Neurosurgeon Performs the First Endoscopic Minimally Invasive Spinal Surgery in Pennsylvania

    Spine disc related low back and leg pain is a major challenge and is the second most common reason that patients visit the doctor in the United States—outnumbered only be respiratory infections—and is the leading cause of disability worldwide. Compression of the spinal nerves is one of the most common diagnoses and is frequently reversible with surgery.

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  • Spying on malaria parasites at -196 Celsius

    MALARIA RESEARCH:  By combining two advanced microscope techniques an international team of scientists led by postdoc Sergey Kapishnikov from the Niels Bohr Institute has managed to obtain new information about the ravaging mode of operation applied by malaria parasites when attacking their victims. This information can be utilized when designing new medication to more effectively fight malaria - a disease claiming over 400.000 lives each year, a majority of whom are infants.

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  • Scientists produce battle-plan blueprints for attacking disease-causing bacteria

    Scientists from Trinity College Dublin have gained key structural insights into the machinery employed by opportunistic, disease-causing bacteria, which may help chemists design new drugs to inhibit them.

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  • Early diagnostic imaging to prevent kidney disease

    Osaka University researchers, in collaboration with several Japanese companies, translate neuroimaging tools to study renal fibrosis in rat kidney. The technique is expected to replace the invasive biopsies currently used to identify patients at risk of developing chronic kidney disease.

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  • Exposure to toxins in e-cig vapor varies depending on scenario

    E-cigarettes are often perceived to be less harmful than their traditional counterparts, but they could still expose the people who “vape” and those around them to harmful compounds. Researchers now report in ACS’ journal Environmental Science & Technology that heavy use and secondhand emissions could lead to inhaled levels of toxins that exceed set exposure limits. But under typical use, secondhand exposure would have a lower impact on health than second- and third-hand cigarette smoke.

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