• Genes, Ozone, and Autism: Increased risk for autism when genetic variation and air pollution meet

    A new analysis shows that individuals with high levels of genetic variation and elevated exposure to ozone in the environment are at an even higher risk for developing autism than would be expected by adding the two risk factors together. The study is the first to look at the combined effects of genome-wide genetic change and environmental risk factors for autism, and the first to identify an interaction between genes and environment that leads to an emergent increase in risk that would not be found by studying these factors independently. A paper describing the research appears online in the journal Autism Research.

    “Autism, like most human diseases, is complex,” said Scott B. Selleck, professor of biochemistry and molecular biology at Penn State and one of the leaders of the research team. “There are probably hundreds, if not thousands, of genes involved and up until now -- with very few exceptions -- these have been studied independently of the environmental contributors to autism, which are real. Our team of researchers represents a merger of people with genetic expertise and environmental epidemiologists, allowing us for the first time to answer questions about how genetic and environmental risk factors for autism interact.”

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  • A Unique Amino Acid for Brain Cancer Therapy

    Photodynamic therapy is often used to treat brain tumors because of its specificity—it can target very small regions containing cancerous cells while sparing the normal cells around it from damage. It works by injecting a drug called a photosensitizer into the bloodstream, where it gathers in cells, and then exposing the drug-filled cells to light. When the photosensitizer is exposed to this light, it emits what is known as a reactive oxygen species (ROS) that causes the cells to die. The method is precise because photosensitizers preferentially gather in cancerous cells over normal cells. As such, when they are exposed to the light, the normal cells will be spared from damage.

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  • Toxic Exposure: Chemicals Are in Our Water, Food, Air and Furniture

    When her kids were young, Tracey Woodruff, PhD, MPH, knew more than most people about environmental toxics. After all, she was a senior scientist at the Environmental Protection Agency (EPA). But even she never dreamed, as she rocked her children to sleep at night, that the plastic baby bottles she used to feed them contained toxic chemicals that could leach into the warm milk. 

    Back then, in the late 1990s, it wasn’t widely known that the chemicals used in plastic sippy cups and baby bottles can potentially disrupt child development by interfering with the hormone system. That, in turn, could alter the functionality of their reproductive systems or increase their risk of disease later in their lives. 

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  • Critical gaps in our knowledge of where infectious diseases occur

    Today Scientists have called for action. The scientific journal Nature ecology & evolution have published a joint statement from scientists at Center for Macroecology, Evolution and Climate, University of Copenhagen and North Carolina State University. The scientists call attention to a serious lack of data on the worldwide distribution of disease-causing organisms. Without this knowledge, predicting where and when the next disease outbreak will emerge is hardly possible. Macroecologists hold the expertise to create the needed data network and close the knowledge gaps.

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  • Burn Without Concern

    The USDA Forest Service in the Boundary Waters Canoe Wilderness Area (BWCWA) will continue to use controlled burns without worrying about fish health in associated watersheds, researchers say.

    “Fire is a part of this community,” said soil scientist Randall Kolka of the USDA Forest Service Northern Research Station, one of the lead authors in the study. “By using it you can lessen the chance of wildfire.”

    Controlled burns prevent wildfires from ripping through the BWCWA in northern Minnesota. The million-acre area encompasses forested hills, wetlands, over 1,100 lakes, and hundreds of miles of streams. Without occasional burns, fallen trees accumulate like matchsticks, creating the perfect environment for uncontrollable wildfires.

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  • Transportation Noise Increases Risk for Cardiovascular Diseases and Diabetes

    How transportation noise affects the health of people remains in many aspects unexplained. Since 2014, an interdisciplinary Swiss consortium has been studying the short- and long-term effects of transportation noise for the population in Switzerland in the frame of the SiRENE study of the Swiss National Science Foundation (SNSF).

    Increased risk for developing cardiovascular diseases

    The results published so far show that aircraft, rail and road traffic noise in Switzerland leads to adverse health effects. For cardiovascular disease mortality, the most distinct association was found for road noise. The risk of dying of a myocardial infarction increases by 4 per cent per 10 decibel increase in road noise at home. Also the risk of hypertension and heart failure increases with transportation noise. "Particularly critical are most likely noise events at night regularly disturbing sleep," says Martin Röösli, principal investigator of SiRENE and professor of environmental epidemiology at Swiss TPH and the University of Basel. "The threshold for negative health impact is lower than previously suspected."

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  • Vibrations can be bad for farmers' backs

    Researcher Catherine Trask and recent master’s graduate Xiaoke Zeng have found that farmers experience prolonged “body shock” when riding horses or driving farming machinery on uneven terrain during an average workday. Whole body vibration is a major risk factor for developing back pain, they say.  

    “Farmers are often unaware that body vibration from machinery use is a potentially harmful physical hazard,” said Trask, U of S Canada Research Chair in Ergonomics and Musculoskeletal Health

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  • Antibacterials in Many Consumer Products Cause More Harm Than Good

    Two antimicrobial chemicals already banned in antiseptic wash products by the U.S. Food and Drug Administration are still found in more than 2,000 widely used consumer products, despite offering no health benefits and actually causing health and environmental harm, according to more than 200 scientists and medical professionals.

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  • African plant extract offers new hope for Alzheimer's treatment

    A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer’s disease, researchers at The University of Nottingham have found.

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  • California Named State with the Worst Air Quality (Again)

    The quality of the air in California may be improving, but it's still dire.

    That's according to the American Lung Association's recent "State of the Air 2017" report, which labeled the state and region a leader in air pollution, with the highest ozone levels.

    The annual study ranks the cleanest and most polluted areas in the country by grading counties in the U.S. based on harmful recorded levels of ozone (smog) and particle pollution. The 2017 report used data collected from 2013 to 2015.

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