Syringe Technology Could Enable Injection Of Concentrated Biologic Drugs

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MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

The technology, which is described in a paper published today in the journal Advanced Healthcare Materials, makes it possible to inject high-concentration drugs and other therapies subcutaneously. It was developed as a solution for highly effective, and extremely concentrated, biopharmaceuticals, or biologics, which typically are diluted and injected intravenously.

“Where drug delivery and biologics are going, injectability is becoming a big bottleneck, preventing formulations that could treat diseases more easily,” says Kripa Varanasi, MIT professor of mechanical engineering. “Drug makers need to focus on what they do best, and formulate drugs, not be stuck by this problem of injectability.”

Read more at Massachusetts Institute of Technology

Image: A new device could help administer powerful drug formulations that are too viscous to be injected with conventional syringes and needles.  Credits: Images courtesy of the researchers and edited by Jose-Luis Olivares, MIT.