Study Shows Delirium Can Signal Presence of COVID-19 in Asymptomatic Older Patients Admitted to the Emergency Department

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A study published today in JAMA Network Open/Emergency Medicine supports evidence that older persons admitted to emergency departments (ED), and subsequently diagnosed positive for COVID-19, often present with delirium when they show no other typical COVID-19 symptoms, such as fever and cough. Sharon K. Inouye, M.D., M.P.H., Director of the Aging Brain Center in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife and Professor of Medicine at Harvard Medical School, is senior author on the study.

A study published today in JAMA Network Open/Emergency Medicine supports evidence that older persons admitted to emergency departments (ED), and subsequently diagnosed positive for COVID-19, often present with delirium when they show no other typical COVID-19 symptoms, such as fever and cough. Sharon K. Inouye, M.D., M.P.H., Director of the Aging Brain Center in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife and Professor of Medicine at Harvard Medical School, is senior author on the study. Co-first authors include Maura Kennedy, M.D., Assistant Professor of Emergency Medicine, Massachusetts General Hospital and Benjamin K. Helfand, M.D., Ph.D. (Cand.), University of Massachusetts Medical School and Warren Alpert Medical School, Brown University.

Although COVID-19 poses a risk at all ages, adults aged 65 years and older are at greatest risk of severe disease, hospitalization, intensive care use, and death. Persons older than 65 years comprise 16 percent of the United States population yet have accounted for more than 80 percent of deaths in the U.S. Delirium is an acute state of confusion, characterized by an altered level of consciousness, disorientation, inattention, and other cognitive disturbances. Beyond COVID-19, delirium is known to be a common symptom in older adults with severe disease in the ED and is associated with extended hospitalization, and increased morbidity and mortality. Despite the threat delirium poses to older ED patients, it is undetected in two-thirds of cases.

Read more at Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research

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